find_nearest_genes: Find the nearest genes for top SNPs in each locus.

In kevinlkx/mapgen: Multi-function software that performs enrichment, functionally-informed genetic fine-mapping and gene mapping

Find the nearest genes for top SNPs in each locus.

Description

Find the nearest genes for top SNPs in each locus.

Usage

find_nearest_genes(
  top.snps,
  genes,
  dist.to = c("genebody", "tss"),
  cols.to.keep = c("snp", "chr", "pos", "nearest_gene")
)

Arguments

top.snps	A GRanges object of the GWAS summary statistics for the top SNPs
genes	A GRanges object of gene information
dist.to	Find nearest genes by distance to gene body or TSS
cols.to.keep	columns to keep in the result

Value

A data frame with SNP locations and nearest genes.

kevinlkx/mapgen documentation built on March 31, 2024, 11:03 p.m.