cosmic_signatures_v3.2: Single base substitution signatures from COSMIC v3.2

Description Usage Format Source

Description

A data set of 78 SBS signatures from COSMIC v3.2 (March 2021). With a few exceptions, these signatures were extracted using SigProfiler (as described in Alexandrov et al., 2020) from the 2,780 whole-genome variant calls produced by the ICGC/TCGA Pan Cancer Analysis of Whole Genomes (PCAWG) Network. The following signatures are annotated as "Possible sequencing artefacts": SBS27, SBS43, SBS45-60.

Usage

1

Format

An object of class matrix with 78 rows and 96 columns.

Source

https://cancer.sanger.ac.uk/cosmic/signatures/SBS/

https://cancer.sanger.ac.uk/signatures/downloads/


kgori/sigfit documentation built on Feb. 3, 2022, 12:04 p.m.