shinyUI(fluidPage(
tags$div(
tags$h2("Polysome association dynamics"),
tags$body(
tags$p(
"Figure 2. published in",
tags$a(
href = 'http://dev.biologists.org/content/early/2017/12/08/dev.159566',
'Cytoplasmic polyadenylation-mediated translational control \
of maternal mRNAs directs maternal to zygotic transition'
),
"Winata CL, Łapiński M et al., Development, 11 December 2017"
),
tags$br(),
tags$p(
"Measurements of transcription (\u2206TS) and translation \
(\u2206TL) rates were obtained as a fraction of total and \
polysome-bound expression values at particular stages compared \
with the egg stage as baseline. Translational regulation is \
defined as a non-linear relationship between transcription and \
translation rates."
),
tags$br(),
tags$div(
align = "center",
tags$em("transcription rate (\u2206TS) = total(stage x) / total(egg)"),
tags$br(),
tags$em("translation rate(\u2206TL) = polysome(stage x) / polysome(egg)"),
tags$br(),
tags$br()
)
)
),
sidebarLayout(
sidebarPanel(
selectInput("data", "Developmental stage:",
names(data),
selected = "1Cell"),
colourpicker::colourInput(
"CPA",
"Maternal CPA colour:",
value = "#FDBF6F",
palette = "limited",
allowedCols = RColorBrewer::brewer.pal(12,
"Paired")
),
colourpicker::colourInput(
"NoCPA",
"Maternal Non-CPA colour:",
value = "#1F78B4",
palette = "limited",
allowedCols = RColorBrewer::brewer.pal(12,
"Paired")
),
sliderInput(
"xlim",
"X axis limits:",
min = -10,
max = 10,
value = c(-5, 5)
),
sliderInput(
"ylim",
"Y axis limits:",
min = -10,
max = 10,
value = c(-5, 5)
),
selectInput(
"type",
"Density plot type:",
c(Histogram = "histogram",
Boxplot = "boxplot"),
selected = "boxplot"
),
conditionalPanel(
condition = "input.type == 'histogram'",
sliderInput(
"bins",
"Number of bins:",
min = 10,
max = 200,
step = 10,
value = 100
)
)
),
mainPanel(
plotOutput(outputId = "scatterplot"),
textOutput(outputId = "desc")
)
)
))
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