tardbpdms_human_disease_mutations: tardbpdms_human_disease_mutations

In lehner-lab/tardbpdms: Analysis scripts for processing TDP-43 DMS data from Bolognesi et al. 2019.

Description

Check fitness bias of human disease mutations.

Usage

tardbpdms_human_disease_mutations(toxicity_dt, missense_AF_file,
  disease_mut_file, outpath, colour_scheme, execute = TRUE)

Arguments

toxicity_dt	data.table with single mutant toxicity values (required)
missense_AF_file	table of missense mutation allele frequencies (required)
disease_mut_file	table of human disease mutations and classifications (required)
outpath	output path for plots and saved objects (required)
colour_scheme	colour scheme file (required)
execute	whether or not to execute the analysis (default: TRUE)

Value

Nothing

lehner-lab/tardbpdms documentation built on July 19, 2019, 7:24 p.m.