getLOH: Compute the number of loss of heterozygosity (LOH) events

Description Usage Arguments Details

View source: R/getLOH.R

Description

Compute the number of loss of heterozygosity (LOH) events

Usage

1
getLOH(seq.dat, min.seg.size = 1.5e+07)

Arguments

seq.dat

a data.frame of the sequencing data

min.seg.size

minimum size of the seqgment

ploidy

the estimated ploidy

Details

raw LOH is calculated as the number of events where: the segment length is greater than the minimum segment size (default of 15e06), and the segment size is less than 90


maxwell-lab/HRDex documentation built on May 3, 2020, 9:01 p.m.