RegressOutResid: Regress out technical effects and cell cycle

In mayer-lab/SeuratForMayer2018: Seurat : R Toolkit for Single Cell Genomics

Description

Remove unwanted effects from scale.data

Usage

RegressOutResid(object, vars.to.regress, genes.regress = NULL,
  model.use = "linear", use.umi = FALSE)

Arguments

object	Seurat object
vars.to.regress	effects to regress out
genes.regress	gene to run regression for (default is all genes)
model.use	Use a linear model or generalized linear model (poisson, negative binomial) for the regression. Options are 'linear' (default), 'poisson', and 'negbinom'
use.umi	Regress on UMI count data. Default is FALSE for linear modeling, but automatically set to TRUE if model.use is 'negbinom' or 'poisson'

Value

Returns the residuals from the regression model

mayer-lab/SeuratForMayer2018 documentation built on May 25, 2019, 9:34 p.m.