drug_target_interaction_example: Drug target interaction example data

Description Usage Format Source

Description

Drug target interaction example data

Usage

1

Format

A named list with 3 items.

target_molecules

Name of layer containing the drug targets. This name has to match the corresponding named item in the list of layers supplied to start_pipeline.

interaction_table

Table giving drug-gene-interactions.

gene_name

Gene names of targeted protein-coding genes.

ncbi_id

NCBI IDs of targeted protein-coding genes.

drug_name

Drug-names with known interactions.

drug_chembl_id

ChEMBL ID of drugs.

match_on

Column name of the data frame supplied in 'interaction_table' that is used for matching drugs and target nodes in the graph (e.g. 'ncbi_id').

Source

Terunuma, Atsushi et al. “MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.” The Journal of clinical investigation vol. 124,1 (2014): 398-412. doi:10.1172/JCI71180

https://www.metabolon.com

Pubchem IDs: https://pubchem.ncbi.nlm.nih.gov

MetaboAnalyst: https://www.metaboanalyst.ca/faces/upload/ConvertView.xhtml


molnet-org/molnet documentation built on Dec. 21, 2021, 8:59 p.m.