initializeEigenanatomy: Convert a matrix to a form that can be used to initialize...

In neuroconductor/ANTsR: ANTs in R: Quantification Tools for Biomedical Images

Description

InitializeEigenanatomy is a helper function to initialize sparseDecom and sparseDecom2. Can be used to estimate sparseness parameters per eigenvector. The user then only chooses nvecs and optional regularization parameters.

Usage

initializeEigenanatomy(initmat, mask = NULL, nreps = 1, smoothing = 0)

Arguments

initmat	input matrix where rows provide initial vector values. alternatively, this can be an antsImage which contains labeled regions.
mask	mask if available
nreps	nrepetitions to use
smoothing	if using an initial label image, optionally smooth each roi

Value

list is output

Author(s)

Avants BB

Examples

mat<-t(replicate(3, rnorm(100)) )
initdf<-initializeEigenanatomy( mat ) # produces a mask
dmat<-replicate(100, rnorm(20)) # data matrix
svdv = t( svd( mat, nu=0, nv=10 )$v )
ilist = matrixToImages( svdv, initdf$mask )
eseg = eigSeg( initdf$mask, ilist,  TRUE  )
eanat<-sparseDecom( dmat, inmask=initdf$mask,
 sparseness=0, smooth=0,
 initializationList=ilist, cthresh=0,
 nvecs=length(ilist) )
initdf2<-initializeEigenanatomy( mat, nreps=2 )
eanat<-sparseDecom( dmat, inmask=initdf$mask,
  sparseness=0, smooth=0, z=-0.5,
  initializationList=initdf2$initlist, cthresh=0,
  nvecs=length(initdf2$initlist) )
# now a regression
eanatMatrix<-eanat$eigenanatomyimages
# 'averages' loosely speaking anyway
myEigenanatomyRegionAverages<-dmat %*% t( eanatMatrix )
dependentvariable<-rnorm( nrow(dmat) )
summary(lm( dependentvariable ~ myEigenanatomyRegionAverages ))

nvox<-1000
dmat<-replicate(nvox, rnorm(20))
dmat2<-replicate(30, rnorm(20))
mat<-t(replicate(3, rnorm(nvox)) )
initdf<-initializeEigenanatomy( mat )
eanat<-sparseDecom2(
 inmatrix = list(dmat,dmat2), 
 inmask=list(initdf$mask,NA),
  sparseness=c( -0.1, -0.2 ), 
  smooth=0,
  initializationList=initdf$initlist, 
  cthresh=c(0,0),
  nvecs=length(initdf$initlist), priorWeight = 0.1 )

neuroconductor/ANTsR documentation built on Oct. 11, 2020, 8:14 a.m.