Description Usage Arguments Value
AUC is calculated through the integrate() function based on dose-response curve.
1 | computeAUC(fit, dmin, dmax, islogd = TRUE)
|
fit |
usually a drFit object. However, any object with a predict method would work. |
dmin |
minimum dose. The integral range is [dmin, dmax]. |
dmax |
maximum dose. The integral range is [dmin, dmax]. |
islogd |
whether the supplied dose dmin/dmax is in log10 scale. The user should be responsible for the consistency between the actual value of dmin, dmax and islogd. If log10 transformed dmin/dmax is supplied with islogd=TRUE, the AUC is calculated based on dose-response curve with x-axis being log10(dose); On the other hand, if dmin, dmax is original scale and islogd=FALSE, the AUC is calculated based on a dose-response curve with x-axis being dose |
a vector of AUC, AUC0 and AUCs. AUC is the area under dose response curve; AUC0 is the area under the line response=1; AUCS is AUC/AUC0
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