computeAUC: Calculate AUC from a fitted object

In nickytong/drexplorer: Dose-response Explorer

Description

AUC is calculated through the integrate() function based on dose-response curve.

Usage

computeAUC(fit, dmin, dmax, islogd = TRUE)

Arguments

fit	usually a drFit object. However, any object with a predict method would work.
dmin	minimum dose. The integral range is [dmin, dmax].
dmax	maximum dose. The integral range is [dmin, dmax].
islogd	whether the supplied dose dmin/dmax is in log10 scale. The user should be responsible for the consistency between the actual value of dmin, dmax and islogd. If log10 transformed dmin/dmax is supplied with islogd=TRUE, the AUC is calculated based on dose-response curve with x-axis being log10(dose); On the other hand, if dmin, dmax is original scale and islogd=FALSE, the AUC is calculated based on a dose-response curve with x-axis being dose

Value

a vector of AUC, AUC0 and AUCs. AUC is the area under dose response curve; AUC0 is the area under the line response=1; AUCS is AUC/AUC0

nickytong/drexplorer documentation built on May 23, 2019, 5:08 p.m.