Description Usage Arguments Value
notice that the median-effect model is a special case of the sigma Emax model; 3 linear models are fitted; fixed ratio thus is required. all 3 linear models are fitted using logit(E) ~ log(d1+d2) using a subset of the data depending on if the data is for durg 1, drug 2 and the mixture
1 2 | fit_median_efect(d1, d2, e, name1 = "Drug A", name2 = "Drug B", d2.d1,
base = exp(1))
|
d1 |
dose for drug 1 |
d2 |
dose for drug 2 |
e |
corresponding response in the range [0, 1] |
name1 |
drug 1 name |
name2 |
drug 2 name |
d2.d1 |
d2/d1, the fixed ratio |
base |
base of logarithm; disabled since the dose-response curve estimation also needs transformation |
a list
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