Description Usage Arguments Value
Identifies differentially expressed genes between two groups of cells using the LRT model proposed in Mcdavid et al, Bioinformatics, 2011
1 2 | diffExp.test(object, cells.1, cells.2, genes.use = NULL,
thresh.use = log(2), print.bar = TRUE)
|
object |
Seurat object |
cells.1 |
Group 1 cells |
cells.2 |
Group 2 cells |
genes.use |
Genes to test. Default is to use all genes. |
thresh.use |
Limit testing to genes which show, on average, at least X-fold difference (log-scale) between the two groups of cells. Increasing thresh.use speeds up the function, but can miss weaker signals. |
print.bar |
Print a progress bar once expression testing begins (uses pbapply to do this) |
Returns a p-value ranked matrix of putative differentially expressed genes.
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