Description Usage Arguments Value
Build augmented structure comprising CM and CP values from coexpression, ME and PE values.
1 2 | build_proxy_structure(proxy_regulon, coexpression, O = NULL,
delta_CM = "auto", delta_CP = "auto")
|
proxy_regulon |
Data frame comprising columns: |
coexpression |
Numerical symmetric matrix providing gene coexpression values. |
O |
Named list where each name is a target candidate and each element is a character vector comprising names of genes that should not be included in the computation of |
delta_CM |
Numerical cutoff point for coexpression module for CM: any values above |
delta_CP |
Numerical cutoff point for coexpression module for CM: any values above |
Data frame implementing augmented structure comprising columns: regulator
, target_candidate
, ortholog_module_status
(1 if orthologous, 0 otherwise), ME
(1 if high affinity for regulator motif, 0 otherwise), PE
(1 if orthologous interaction, 0 otherwise), CM
and CP
.
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