mpepLFQ: LFQ of peptides

mpepLFQR Documentation

LFQ of peptides

Description

Peptides are shared by species.

Usage

mpepLFQ(
  basenames,
  are_refs,
  are_smpls,
  xsmat,
  ysmat,
  tsmat,
  ssmat,
  mmat,
  pmat,
  mbr_peps,
  sp_centers,
  pri_sps = 0L,
  new_na_species = ".other",
  rt_tol = 30,
  mbr_ret_tol = 30,
  step = 0.005,
  lfq_mbr = TRUE,
  err_log2r = 0.25
)

Arguments

basenames

The base names of a peptide table files (TMTset[i]_LCMSinj[j]_Peptide_N.txt).

are_refs

Logical; are references or not.

are_smpls

Logical; are samples or not.

xsmat

A matrix of m-over-z values.

ysmat

A matrix of apex intensities.

tsmat

A matrix of apex retention times.

ssmat

A matrix of apex scan numbers.

mmat

A logical matrix of MBR status.

pmat

A confounding matrix or vectors of peptides shared across species.

mbr_peps

A vector of pep_seq_modz sequences in the universe.

sp_centers

The centers of log2FC for each species; names: species, values: log2FC.

pri_sps

A primary species.

new_na_species

A replace value for NA species.

rt_tol

Error tolerance in retention times.

mbr_ret_tol

The tolerance in MBR retention time in seconds.

step

The step size in binning retention times.

lfq_mbr

Logical; perform LFQ-MBR or not.

err_log2r

Not yet used. Error tolerance in log2FC.


qzhang503/proteoQ documentation built on Feb. 27, 2025, 8:34 a.m.