calc_egfr: Calculate eGFR

In ronkeizer/clinPK: Clinical Pharmacokinetics Toolkit

Description

Calculate the estimated glomerulal filtration rate (an estimate of renal function) based on measured serum creatinine using one of the following approaches: - Cockcroft-Gault (using weight, ideal body weight, or adjusted body weight) - Revised Lund-Malmo - Modification of Diet in Renal Disease study (MDRD) - Schwartz - Schwartz revised - Jelliffe - Jelliffe (for unstable renal function) - Wright

Usage

calc_egfr(method = "cockcroft_gault", sex = NULL, age = NULL,
  scr = NULL, scr_unit = NULL, scr_assay = NULL, race = "other",
  weight = NULL, height = NULL, bsa = NULL, preterm = FALSE,
  ckd = FALSE, times = NULL, bsa_method = "dubois", relative = NULL,
  unit_out = "mL/min", ...)

Arguments

method	eGFR estimation method, choose from 'cockcroft_gault', 'cockcroft_gault_ideal', 'mdrd', 'ckd_epi', malmo_lund_revised', 'schwartz', 'jelliffe', 'jellife_unstable', 'wright'
sex	sex
age	age
scr	serum creatinine (mg/dL)
scr_unit,	'mg/dL' or 'micromol/L' (=='umol/L')
scr_assay,	'jaffe' or 'enzymatic' or 'idms'
race	'black' or 'other'
weight	weight
height	height, only relevant when converting to/from BSA-relative unit
bsa	body surface area
preterm	is patient preterm?
ckd	chronic kidney disease? (Schwartz equations only)
times	vector of sampling times for creatinine (only used in Jelliffe equation for unstable patients)
bsa_method	BSA estimation method, see 'bsa()' for details
relative	'TRUE'/'FALSE'. Report eGFR as per 1.73 m2? Requires BSA if re-calculation required. If 'NULL' (=default), will choose value typical for 'method'.
unit_out	'ml/min' (default), 'L/hr', or 'mL/hr'
...	arguments passed on

Details

Equations for estimation of eGFR from Cystatin C concentrations are available from the 'calc_egfr_cystatin()' function.

Examples

calc_egfr(sex = "male", age = 50, scr = 1.1, weight = 70)
calc_egfr(sex = "male", age = 50, scr = 1.1, weight = 70, unit_out = "L/hr")
calc_egfr(sex = "male", age = 50, scr = 1.1, weight = 70, bsa = 1.8, method = "ckd_epi")
calc_egfr(sex = "male", age = 50, scr = c(1.1, 0.8),
  weight = 70, height = 170, method = "jelliffe")
calc_egfr(sex = "male", age = 50, scr = c(1.1, 0.8),
  weight = 70, height = 170, method = "jelliffe_unstable")
calc_egfr(sex = "male", age = 50, scr = 1.1,
  weight = 70, bsa = 1.6, method = "malmo_lund_rev", relative = FALSE)

ronkeizer/clinPK documentation built on May 20, 2019, 5:07 p.m.