nca: Perform an NCA based on a NONMEM-style dataset

In ronkeizer/clinPK: Clinical Pharmacokinetics Toolkit

Description

Perform an NCA based on a NONMEM-style dataset

Usage

nca(data = NULL, dose = 100, tau = 6, method = "log_linear",
  scale = list(auc = 1, conc = 1), dv_min = 0.001)

Arguments

data	data.frame with time and dv columns
dose	dose amount
tau	dosing frequency
method	'log_linear' or 'linear'
scale	list with scaling for auc and concentration ('conc')
dv_min	minimum concentrations, lower observations will be set to this value

Examples

data <- data.frame(time = c(0, 2, 4, 6, 8, 12, 16),
                   dv   = c(0, 10, 14, 11, 9, 5, 1.5))
nca(data)

ronkeizer/clinPK documentation built on May 20, 2019, 5:07 p.m.