Description Usage Arguments Examples
Calculate dose to achieve steady state Cmax for 2-compartmental PK model bolus dosing at steady state
1 2 | pk_2cmt_bolus_dose_from_cmax(cmax = 1, tau = 12, CL = 3, V = 30,
Q = 2, V2 = 20)
|
cmax |
desired trough concentration |
tau |
dosing interval |
CL |
clearance |
V |
volume of distribution |
Q |
inter-compartimental clearance |
V2 |
volume of peripheral compartment |
1 2 3 4 | dos <- pk_2cmt_bolus_dose_from_cmax(
cmax = 10, tau = 12,
CL = 5, V = 50, Q = 20, V2 = 200)
find_nearest_dose(dos, 100)
|
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