get_normalized_responses: Find normalised receptor responses

In ropensci/DoOR.functions: Integrating Heterogeneous Odorant Response Data into a Common Response Model: A DoOR to the Complete Olfactome

Find normalised receptor responses

Description

given a chemical, get normalised receptor responses from all studies in the database.

Usage

get_normalized_responses(odors, zero = door_default_values("zero"),
  response_matrix = door_default_values("door_response_matrix"), round = 3,
  na.rm = FALSE)

Arguments

odors	character vector, one or more odors provided as InChIKey.
zero	InChIKey of background that should be set to zero. The default is "SFR", i.e. the spontaneous firing rate.
response_matrix	a data frame, as e.g. "door_response_matrix" that is loaded by model_response. It is also possible to create this frame manually using model_response.
round	numeric, round to this amount of digits, set to NA if you do not want to round
na.rm	logical, remove NAs?

Author(s)

Daniel Münch [e-mail]

See Also

model_response,create_door_database

Examples

# load data
library(DoOR.data)
data(door_response_matrix)

# define a list of odorants
odors <- c("MLFHJEHSLIIPHL-UHFFFAOYSA-N",
           "OBNCKNCVKJNDBV-UHFFFAOYSA-N",
           "IKHGUXGNUITLKF-UHFFFAOYSA-N")

# get the normalized responses for these odorants
result <- get_normalized_responses(odors, 
                                   response_matrix = door_response_matrix)

ropensci/DoOR.functions documentation built on Feb. 22, 2024, 9:44 a.m.