getb0.biseq: compute b0, projection matrix, given methylation counts

In rosedu1/deconvSeq: Cell Type Deconvolution for RNA Sequencing and Bisulfite Sequencing

Description

compute b0, projection matrix, given methylation counts

Usage

getb0.biseq(methmat, design, sigg = NULL)

Arguments

methmat	a matrix of counts with rows corresponding to methylation sites and columns. Columns are: chr start end strand coverage1 numCs1 numTs1 coverage2 numCs2 numTs2 ....
design	design matrix, output of model.matrix
sigg	predetermined signature CpG sites. Format sites as chromosome name, chromosome location, strand: chrN_position(+/-). For example, chr1_906825-

Value

b0 projection matrix. Coefficients are beta.

Examples

## Not run: 
data("data_celltypes_rrbs") 
b0.rrbs = getb0.biseq(methmat, design.rrbs, sigg=NULL)

## End(Not run)

rosedu1/deconvSeq documentation built on Aug. 19, 2020, 7:10 p.m.