Description Usage Arguments Value Examples
Find overall maximum LOD score in genome scan results, across all positions and columns.
1 |
scan1_output |
An object of class |
map |
A list of vectors of marker positions, as produced by
|
chr |
Option vector of chromosomes to consider. |
A single number: the maximum LOD score across all columns and positions for the selected chromosomes.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 | ## Not run:
# load qtl2geno package for data and genoprob calculation
library(qtl2geno)
# read data
iron <- read_cross2(system.file("extdata", "iron.zip", package="qtl2geno"))
# insert pseudomarkers into map
map <- insert_pseudomarkers(iron$gmap, step=1)
# calculate genotype probabilities
probs <- calc_genoprob(iron, map, error_prob=0.002)
# grab phenotypes and covariates; ensure that covariates have names attribute
pheno <- iron$pheno
covar <- match(iron$covar$sex, c("f", "m")) # make numeric
names(covar) <- rownames(iron$covar)
Xcovar <- get_x_covar(iron)
# perform genome scan
out <- scan1(probs, pheno, addcovar=covar, Xcovar=Xcovar)
# overall maximum
maxlod(out)
# maximum on chromosome 2
maxlod(out, map, "2")
## End(Not run)
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