shubham1637/DIAlignR: Dynamic Programming Based Alignment of MS2 Chromatograms

To obtain unbiased proteome coverage from a biological sample, mass-spectrometer is operated in Data Independent Acquisition (DIA) mode. Alignment of these DIA runs establishes consistency and less missing values in complete data-matrix. This package implements dynamic programming with affine gap penalty based approach for pair-wise alignment of analytes. A hybrid approach of global alignment (through MS2 features) and local alignment (with MS2 chromatograms) is implemented in this tool.

Getting started

Package details

Bioconductor views Alignment MassSpectrometry Metabolomics Proteomics Software
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
shubham1637/DIAlignR documentation built on May 29, 2021, 12:45 p.m.