editor_options: markdown: wrap: 72
oncoEnrichR is an R package for functional interrogation of human genesets in the context of cancer. It is primarily intended for exploratory analysis, interpretation, and prioritization of long gene lists, which represent a common output from many types of high-throughput cancer biology screens.
oncoEnrichR can be used to interrogate results from e.g. genetic screens (siRNA/CRISPR), protein proximity labeling, or transcriptomics (differential expression). The tool queries a variety of high-quality data resources in order to assemble useful gene annotations and analyses in an interactive report (examples from the report shown below).
Web-based access to oncoEnrichR is available at https://oncotools.elixir.no
The contents of the analysis report provided by oncoEnrichR address the following scientific questions for a given gene list:
See also the output views that addresses each of the questions above.
If you use oncoEnrichR, please cite the following publication:
Sigve Nakken, Sveinung Gundersen, Fabian L. M. Bernal, Dimitris Polychronopoulos, Eivind Hovig, and Jørgen Wesche. Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR (2023). Int J Cancer. doi:10.1002/ijc.34666
sigven AT ifi.uio.no
oncoEnrichR is supported by the Centre for Cancer Cell Reprogramming at the University of Oslo/Oslo University Hospital, and Elixir Norway (Oslo node).
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.