sjczheng/EpiDISH: Epigenetic Dissection of Intra-Sample-Heterogeneity

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of whole blood, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Getting started

Package details

AuthorAndrew E. Teschendorff <a.teschendorff@ucl.ac.uk>, Shijie C. Zheng<shijieczheng@gmail.com>
Bioconductor views DNAMethylation DifferentialMethylation Epigenetics ImmunoOncology MethylationArray
MaintainerShijie Charles Zheng<shijieczheng@gmail.com>
LicenseGPL-2
Version2.3.2
URL https://github.com/sjczheng/EpiDISH
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("sjczheng/EpiDISH")
sjczheng/EpiDISH documentation built on March 7, 2020, 8:06 p.m.