test_limma_lm: Automatic differential gene expression using limma

In ssarda/genomeutils: Utilities for Genome Analysis

Description

This function tests for differential expression per gene using a linear model and definition contrasts that splits the input matrix into groups of samples. It outputs the fit, coefficients per gene, as well as the sum of residual squares after accounting for weights.

Usage

test_limma_lm(mat, mod, weights)

Arguments

mat	A gene expression matrix (genes x samples)
weights	Assign differential weights either across genes or samples
model	A model of contrasts splitting samples

Value

It outputs a list with the model fit, coefficients per gene, as well as the sum of residual squares after accounting for differential weights

ssarda/genomeutils documentation built on May 30, 2019, 8:42 a.m.