README.md

In thijsjanzen/isoSIM: Simulate Linkage Disequilibrium Along Chromosomes in Isofemale Lines

isoSIM

Genetic admixture simulation for isofemale lines and further

What is isoSIM?

isoSIM is the predecessor of GenomeAdmixR. Where isoSIM started as a package designed to track ancestry in the creation of isofemale lines.

Demonstration isoSIM

Thijs Janzen gave a presentation demonstrating isoSIM at the R User Group at the University of Groningen, Groningen, The Netherlands. You can watch his presentation here (audio starts after 1 min)

Version history

Version 0.57 - Added function to generate admixed individuals Version 0.56 - Added starting frequencies to 'simulate_admixture' Version 0.55 - extended 'calculate_marker_frequency' to handle a vector of locations Version 0.55 - increased accuracy of choosing a random position for recombination, this should prevent the rare bug fixed in version 0.54 Version 0.54 - Fixed a MAJOR bug regarding recombination: in rare cases, a crossover position could be picked on an existing junction, due to the limited number of digits in uniform() Version 0.54 - Improved plot_difference_frequencies to handle modified input Version 0.53 - Added multiplicative_selection Version 0.52 - Added plot_difference_frequencies Version 0.51 - Added tajima's d calculation Version 0.50 - added simulated_admixture until Version 0.49 - Added 'simulate' to cpp Version 0.48 - Added a general 'simulate' function Version 0.47 - Changed the effect of migration Version 0.46 - Added joyplot & increase_ancestor Version 0.45 - Removed create_two_populations Version 0.44 - Added tracking regions Version 0.43 - Fixed bugs in select_population Version 0.42 - Added initial and final frequency tables Version 0.41 - Added multiple marker support Version 0.40 - Collapsed selection functions Version 0.39 - Added support for non-additive selection Version 0.38 - Added track frequencies Version 0.37 - Removed selection on regions Version 0.36 - Added progress_bar option Version 0.35 - Added calculate_marker_frequency Version 0.34 - Added selection_markers Version 0.33 - Fixed bugs in selection Version 0.32 - Moved Fish.h code to Fish.cpp Version 0.31 - Changed random number generator to R based Version 0.30 - Added Recombination = 1 code Version 0.29 - Changed internal junction representation: removed .left Version 0.28 - Reverted to Agner Fog Random number generation Version 0.27 - Speed up return types Version 0.26 - Added class verification code Version 0.25 - Squashed plotting bug Version 0.24 - Removed Output.cpp Version 0.23 - Removed number_of_founders from calc_allele_spectrum Version 0.22 - Added save and load functions Version 0.21 - Changed random-seed management Version 0.20 - Removed superfluous code Version 0.19 - Removed number_of_founders from Fst and LD code Version 0.18 - Start of tracking changes

thijsjanzen/isoSIM documentation built on May 29, 2019, 10:39 a.m.