callBafChanges: Call sites showing BAF changes

Description Usage Arguments

Description

This function performs very crude mutation calling based on BAFs. The calling is depends only on fold change and minimum AF thresholds.

Usage

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callBafChanges(baftable, cref, csample, foldchange = 1.2, maxref = 0.05,
  minAF = 0.15)

Arguments

baftable

data.frame with variants and allelic frequencies

cref

identifier for column with reference BAF (e.g. normal tissue)

csample

identifier for column with matched sample BAF (e.g. tumor tissue)

foldchange

minimum fold.change threshold to call mutation

maxref

numeric, maximum allowed BAF in the reference sample

minAF

numeric, minimum BAF required in the sample


tkonopka/RGeneticThesaurus documentation built on May 31, 2019, 3:44 p.m.