mega_model: MEGA MODEL

In tsoleary/proteomixr: Label-free quantitative proteomics & D3-Leu turnover

Description

Creates a data frame with the change of individual isotopes over time

Usage

mega_model(peptide, deg_old, deg_new, syn, t0_abun, per_lab, time)

Arguments

peptide	peptide containing Leucine
deg_old	degradation rate constant (k) of the "old" material around at the beginning of the experiment
deg_new	degradation rate constant (k) of newly synthesized material
syn	synthesis rate (amount/time)
t0_abun	initial abundance
per_lab	percent of D3-Leu in the labeled growth media
time	vector of time to be modeled (e.g. 0:168)

Examples

# initial conditions
peptide <- "SAMPLLLLLLER"

# initial total abundance at T0
t0_abun <- 1000

# fraction of labeled Leucine in the media
per_lab <- 0.50

# rates
deg_old <- 0.0500
deg_new <- 0.0500
syn <- 50

# length of time
time <- 0:168

mod <- mega_model(peptide, deg_old, deg_new, syn, t0_abun, per_lab, time)

tsoleary/proteomixr documentation built on July 19, 2019, 8:37 a.m.