Description Usage Arguments Details Value References See Also
Implements a Logan plot, or Logan graphical analysis, a "graphical method of analysis applicable to ligands that bind reversibly to receptors or enzymes requiring the simultaneous measurement of plasma and tissue radioactivities for multiple times after the injection of a radiolabeled tracer is presented".
1 2 | logan.plot(input.function, tissue, time.start, time.end,
plot = TRUE, ...)
|
input.function |
Input function TAC. |
tissue |
Tissue TAC. |
time.start |
Initial acquisition time for each frame. |
time.end |
Final acquisition time for each frame. |
plot |
Should the Logan plot be displayed? Defaults
to |
... |
Additional parameters passed to the
|
Please refer to the documentation of
processlinear
for implementation details.
Returns a list with three fields: kparms
, the
computed kinetic parameters; stderrors
, the
standard errors for each parameter as a percentage;
fit
, the actual fitted object.
J. Logan, J. S. Fowler, N. D. Volkow, A. P. Wolf, S. L. Dewey, D. J. Schlyer, R. R. MacGregor, R. Hitzemann, B. Bendriem, and S. J. Gatley, "Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects.," Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol. 10, no. 5, pp. 740-7, Sep. 1990.
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