nh3.2c.fit: Computes the one-tissue compartmental model parameters for...

In traceRkinetic: Kinetic analysis for dynamic nuclear imaging: compartmental models

Description

Automatically performs the metabolite correction implemented in nh3.vdhoff.correction to the input.function term. The left.ventricle term is not provided. All the other parameters are provided just like in the irreversible.2c.fit function and the return values are the same.

Usage

  nh3.2c.fit(input.function, tissue, time.start, time.end,
    K1.start = 0.1, K1.lower = 0, K1.upper = 8,
    k2.start = 0.1, k2.lower = 0, k2.upper = 8,
    k3.start = 0.1, k3.lower = 0, k3.upper = 8,
    vB.start = 0.05, vB.lower = 0, vB.upper = 1,
    weight = time.end - time.start, plot = FALSE,
    interpolation.type = 1, ...)

Arguments

input.function	Input function TAC.
tissue	Tissue TAC.
time.start	Initial acquisition time for each frame (in minutes).
time.end	Final acquisition time for each frame (in minutes).
K1.start,k2.start,k3.start,vB.start	Initial parameter values.
K1.lower,k2.lower,k3.lower,vB.lower	Parameter lower bounds.
K1.upper,k2.upper,k3.upper,vB.upper	Parameter upper bounds.
weight	Weight vector for the non-linear squares fit. Defaults to frame length.
plot	TRUE if a plot is to be shown. Defaults to FALSE.
interpolation.type	Interpolation type selection. Passed to interpolate.tac. Defaults to 1.
...	Other parameters passed to the plot function, if used.

Value

Returns a list with three fields: kparms, the computed kinetic parameters; stderrors, the standard errors for each parameter as a percentage; fit, the actual fitted object.

traceRkinetic documentation built on May 2, 2019, 6:10 p.m.