Fits the model implemented in
reversible.2c.model
.
1 2 3 4 5 6 7 8 9  reversible.2c.fit(input.function, tissue, time.start,
time.end, K1.start = 0.1, K1.lower = 0, K1.upper = 8,
k2.start = 0.1, k2.lower = 0, k2.upper = 8,
k3.start = 0.01, k3.lower = 0, k3.upper = 8,
k4.start = 0.01, k4.lower = 0, k4.upper = 8,
vB.start = 0.05, vB.lower = 0, vB.upper = 1,
left.ventricle = input.function,
weight = time.end  time.start, plot = FALSE,
interpolation.type = 1, ...)

input.function 
Input function TAC. 
tissue 
Tissue TAC. 
time.start 
Initial acquisition time for each frame (in minutes). 
time.end 
Final acquisition time for each frame (in minutes). 
K1.start,k2.start,k3.start,k4.start,vB.start 
Initial parameter values. 
K1.lower,k2.lower,k3.lower,k4.lower,vB.lower 
Parameter lower bounds. 
K1.upper,k2.upper,k3.upper,k4.upper,vB.upper 
Parameter upper bounds. 
left.ventricle 
Left ventricle TAC, used for
spillover corretion. Defaults to

weight 
Weight vector for the nonlinear squares fit. Defaults to frame length. 
plot 

interpolation.type 
Interpolation type selection.
Passed to 
... 
Other parameters passed to the plot function, if used. 
Returns a list with three fields: kparms
, the
computed kinetic parameters; stderrors
, the
standard errors for each parameter as a percentage;
fit
, the actual fitted object.
Questions? Problems? Suggestions? Tweet to @rdrrHQ or email at ian@mutexlabs.com.
All documentation is copyright its authors; we didn't write any of that.