reversible.2c.fit: Reversible two-tissue compartment model fit

In traceRkinetic: Kinetic analysis for dynamic nuclear imaging: compartmental models

Description

Fits the model implemented in reversible.2c.model.

Usage

  reversible.2c.fit(input.function, tissue, time.start,
    time.end, K1.start = 0.1, K1.lower = 0, K1.upper = 8,
    k2.start = 0.1, k2.lower = 0, k2.upper = 8,
    k3.start = 0.01, k3.lower = 0, k3.upper = 8,
    k4.start = 0.01, k4.lower = 0, k4.upper = 8,
    vB.start = 0.05, vB.lower = 0, vB.upper = 1,
    left.ventricle = input.function,
    weight = time.end - time.start, plot = FALSE,
    interpolation.type = 1, ...)

Arguments

input.function	Input function TAC.
tissue	Tissue TAC.
time.start	Initial acquisition time for each frame (in minutes).
time.end	Final acquisition time for each frame (in minutes).
K1.start,k2.start,k3.start,k4.start,vB.start	Initial parameter values.
K1.lower,k2.lower,k3.lower,k4.lower,vB.lower	Parameter lower bounds.
K1.upper,k2.upper,k3.upper,k4.upper,vB.upper	Parameter upper bounds.
left.ventricle	Left ventricle TAC, used for spill-over corretion. Defaults to input.function.
weight	Weight vector for the non-linear squares fit. Defaults to frame length.
plot	TRUE if a plot is to be shown. Defaults to FALSE.
interpolation.type	Interpolation type selection. Passed to interpolate.tac. Defaults to 1.
...	Other parameters passed to the plot function, if used.

Value

Returns a list with three fields: kparms, the computed kinetic parameters; stderrors, the standard errors for each parameter as a percentage; fit, the actual fitted object.

traceRkinetic documentation built on May 2, 2019, 6:10 p.m.