lortie.fit: Lortie et al. (2007) model fit.

In traceRkinetic: Kinetic analysis for dynamic nuclear imaging: compartmental models

Description

Fits the one-tissue compatment 82-rubidium model implemented in lortie.model.

Usage

  lortie.fit(input.function, tissue, time.start, time.end,
    a = 0.77, b = 0.63, FLV.start = 0.1, FLV.lower = 0,
    FLV.upper = 1, flow.start = 0.5, flow.lower = 0,
    flow.upper = 8, k2.start = 0.1, k2.lower = 0,
    k2.upper = 8, left.ventricle = input.function,
    weight = time.end - time.start, plot = FALSE,
    interpolation.type = 1, ...)

Arguments

input.function	Input function TAC (typically, left ventricle).
tissue	Tissue (myocardium) TAC.
time.start	Initial time for each frame (in minutes).
time.end	End time for each frame (in minutes).
a	Parameter a of the Renkin-Crone equation implemented in flow2k1. Defaults to 0.77 [unitless].
b	Parameter b of the Renkin-Crone equation implemented in flow2k1. Defaults to 0.63 [ml/min/g].
FLV.start,flow.start,k2.start	Initial parameter values for the non-linear squares fitting.
FLV.lower,flow.lower,k2.lower	Lower bounds.
FLV.upper,flow.upper,k2.upper	Upper bounds.
left.ventricle	Left ventricle TAC, used for spill-over corretion. Defaults to input.function.
weight	Weights for the non-linear least squares. Defaults to frame length.
plot	Should the results be plotted. Defaults to FALSE.
interpolation.type	Interpolation type selection. Passed to interpolate.tac. Defaults to 1.
...	If plotting is used, optional parameters are passed to the plot function.

Value

Returns a list with three fields: kparms, the computed kinetic parameters; stderrors, the standard errors for each parameter as a percentage; fit, the actual fitted object.

traceRkinetic documentation built on May 2, 2019, 6:10 p.m.