getGroupGO: Functional Profile of a gene set at specific GO level

In CeTF: Coexpression for Transcription Factors using Regulatory Impact Factors and Partial Correlation and Information Theory analysis

Description

Functional Profile of a gene set at specific GO level. Given a vector of genes, this function will return the GO profile at a specific level.

Usage

getGroupGO(genes, ont = "BP", keyType, annoPkg, level = 3)

Arguments

genes	Character vector with the genes to perform the functional profile.
ont	One of 'MF', 'BP', and 'CC' subontologies (default: 'BP').
keyType	Key type of inputted genes (i.e. 'ENSEMBL', 'SYMBOL', 'ENTREZID').
annoPkg	Package of annotation of specific organism (i.e. org.Hs.eg.db, org.Bt.eg.db, org.Rn.eg.db, etc).
level	Specific GO Level (default: 3).

Value

Returns an list with the results of the functional profile of the genes and a network with the ontologies (column 1) and the corresponding genes (column 2).

Examples

## Not run:  
# load the annotation package
library(org.Hs.eg.db)

# load the CeTF class object resulted from runAnalysis function
data(CeTFdemo)

# getting the genes in network of condition 1
genes <- unique(c(as.character(NetworkData(CeTFdemo, 'network1')[, 'gene1']),
                 as.character(NetworkData(CeTFdemo, 'network1')[, 'gene2'])))

# performing getGroupGO analysis
cond1 <- getGroupGO(genes = genes,
                    ont = 'BP',
                    keyType = 'ENSEMBL',
                    annoPkg = org.Hs.eg.db, 
                    level = 3)

## End(Not run)

CeTF documentation built on Nov. 25, 2020, 2 a.m.