Harman is a PCA and constrained optimisation based technique that maximises the removal of batch effects from datasets, with the constraint that the probability of overcorrection (i.e. removing genuine biological signal along with batch noise) is kept to a fraction which is set by the end-user.
|Author||Josh Bowden [aut], Jason Ross [aut, cre], Yalchin Oytam [aut]|
|Bioconductor views||BatchEffect DNAMethylation Microarray MultipleComparison Normalization Preprocessing PrincipalComponent Software StatisticalMethod Transcription|
|Maintainer||Jason Ross <[email protected]>|
|License||GPL-3 + file LICENCE|
|Package repository||View on Bioconductor|
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