Harman: The removal of batch effects from datasets using a PCA and constrained optimisation based technique

Harman is a PCA and constrained optimisation based technique that maximises the removal of batch effects from datasets, with the constraint that the probability of overcorrection (i.e. removing genuine biological signal along with batch noise) is kept to a fraction which is set by the end-user.

Package details

AuthorJosh Bowden [aut], Jason Ross [aut, cre], Yalchin Oytam [aut]
Bioconductor views BatchEffect DNAMethylation Microarray MultipleComparison Normalization Preprocessing PrincipalComponent Software StatisticalMethod Transcription
MaintainerJason Ross <jason.ross@csiro.au>
LicenseGPL-3 + file LICENCE
URL http://www.bioinformatics.csiro.au/harman/
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


Try the Harman package in your browser

Any scripts or data that you put into this service are public.

Harman documentation built on Nov. 8, 2020, 7:50 p.m.