LineagePulse is a differential expression and expression model fitting package tailored to single-cell RNA-seq data (scRNA-seq). LineagePulse accounts for batch effects, drop-out and variable sequencing depth. One can use LineagePulse to perform longitudinal differential expression analysis across pseudotime as a continuous coordinate or between discrete groups of cells (e.g. pre-defined clusters or experimental conditions). Expression model fits can be directly extracted from LineagePulse.
|David S Fischer [aut, cre], Fabian Theis [ctb], Nir Yosef [ctb]
|CellBasedAssays CellBiology DifferentialExpression GeneExpression ImmunoOncology Sequencing SingleCell Software StatisticalMethod TimeCourse
|David S Fischer <email@example.com>
|View on Bioconductor
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