Standardization in regards to selected time-point

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Description

Standardisation of the expression values of every gene is performed, so that the expression values at a chosen time point are zero and the standard deviations are one.

Usage

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standardise2(eset,timepoint=1)

Arguments

eset

object of the class ExpressionSet.

timepoint

integer: which time point should have expression values of zero.

Value

The function produces an object of the ExpressionSet class with standardised expression values.

Author(s)

Matthias E. Futschik (http://itb.biologie.hu-berlin.de/~futschik)

Examples

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if (interactive()){
data(yeast)
# Data pre-processing
yeastF <- filter.NA(yeast)
yeastF <- fill.NA(yeastF)
yeastF <- standardise2(yeastF,timepoint=1)

# Soft clustering and visualisation
cl <- mfuzz(yeastF,c=20,m=1.25)
mfuzz.plot(yeastF,cl=cl,mfrow=c(4,5))
}

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