permNULL: Do permutations for input rich phenotyping screens.

In PANR: Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations

Description

This is an internal S4 method for class PAN to permute the original inputted phenotyping screens to further fit the dissociation component of the beta-mixture model.

Usage

permNULL(object, permMethod="keepRep", ...)

Arguments

object	an object of BetaMixture.
permMethod	a character value of the method to permute, either 'keepRep' (keep the order of replicates) or 'all' (regardless of replicates).

Value

a matrix of permuted data.

Author(s)

Xin Wang [e-mail]

References

Xin Wang, Mauro Castro, Klaas W. Mulder and Florian Markowetz, Posterior association networks and enriched functional gene modules inferred from rich phenotypic perturbation screens, in preparation.

See Also

fitNULL, fitBM, BetaMixture

Examples

data(bm)
bm.perm<-permNULL(bm1)

PANR documentation built on Nov. 8, 2020, 8:15 p.m.