Do permutations for input rich phenotyping screens.

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Description

This is an internal S4 method for class PAN to permute the original inputted phenotyping screens to further fit the dissociation component of the beta-mixture model.

Usage

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permNULL(object, permMethod="keepRep", ...)

Arguments

object

an object of BetaMixture.

permMethod

a character value of the method to permute, either 'keepRep' (keep the order of replicates) or 'all' (regardless of replicates).

Value

a matrix of permuted data.

Author(s)

Xin Wang xw264@cam.ac.uk

References

Xin Wang, Mauro Castro, Klaas W. Mulder and Florian Markowetz, Posterior association networks and enriched functional gene modules inferred from rich phenotypic perturbation screens, in preparation.

See Also

fitNULL, fitBM, BetaMixture

Examples

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data(bm)
bm.perm<-permNULL(bm1)