computeAmax: Fits dose-response curves to data given by the user and...
In PharmacoGx: Analysis of Large-Scale Pharmacogenomic Data

Description Usage Arguments Value Examples

Fits dose-response curves to data given by the user and returns the Amax of the fitted curve. Amax: 100 - viability at maximum concentarion (in fitted curve)

1	computeAmax(concentration, viability, trunc = TRUE, verbose = FALSE)

`concentration`	[vector] is a vector of drug concentrations.
`viability`	[vector] is a vector whose entries are the viability values observed in the presence of the drug concentrations whose logarithms are in the corresponding entries of the log_conc, expressed as percentages of viability in the absence of any drug.
`trunc`	[logical], if true, causes viability data to be truncated to lie between 0 and 1 before curve-fitting is performed.
`verbose`	[logical] should warnings be printed

The numerical Amax

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dose <- c("0.0025","0.008","0.025","0.08","0.25","0.8","2.53","8") 
viability <- c("108.67","111","102.16","100.27","90","87","74","57")
computeAmax(dose, viability)