PureCN: Copy number calling and SNV classification using targeted short read sequencing

This package estimates tumor purity, copy number, and loss of heterozygosity (LOH), and classifies single nucleotide variants (SNVs) by somatic status and clonality. PureCN is designed for targeted short read sequencing data, integrates well with standard somatic variant detection and copy number pipelines, and has support for tumor samples without matching normal samples.

Package details

AuthorMarkus Riester [aut, cre] (<https://orcid.org/0000-0002-4759-8332>), Angad P. Singh [aut]
Bioconductor views CopyNumberVariation Coverage ImmunoOncology Sequencing Software VariantAnnotation VariantDetection
MaintainerMarkus Riester <markus.riester@novartis.com>
URL https://github.com/lima1/PureCN
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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PureCN documentation built on Nov. 8, 2020, 5:37 p.m.