initialize-RnBDiffMeth-method: initialize.RnBDiffMeth

Description Usage Arguments Author(s)

Description

Initialize an RnBDiffMeth object

Usage

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## S4 method for signature 'RnBDiffMeth'
initialize(
  .Object,
  site.test.method = rnb.getOption("differential.site.test.method"),
  variability.method = rnb.getOption("differential.variability.method"),
  covg.thres = rnb.getOption("filtering.coverage.threshold"),
  disk.dump = FALSE,
  disk.path = NULL
)

Arguments

.Object

New instance of RnBDiffMeth.

site.test.method

method which was applied to obtain the site-level p-values.

variability.method

method to be used to calculate differentially variable sites. Has to be one of: ‘diffVar’ or ‘iEVORA’.

covg.thres

coverage threshold. Important for certain columns of the differential methylation tables. See computeDiffMeth.bin.site and computeDiffMeth.bin.region for details.

disk.dump

Flag indicating whether the tables should be stored on disk rather than in the main memory

disk.path

Path on the disk for DMTs.Only meaningful if disk.dump is TRUE

Author(s)

Fabian Mueller


RnBeads documentation built on March 3, 2021, 2 a.m.