TPP: Thermal proteome profiling (TPP)

Description Usage Arguments Details Value References

Description

TPP is a toolbox for analyzing thermal proteome profiling (TPP) experiments.

Usage

1
.onLoad(libname, pkgname)

Arguments

libname

a character string giving the library directory where the package defining the namespace was found. Passed to .onLoad function.

pkgname

a character string giving the name of the package. Passed to .onLoad function.

Details

In order to start a TPP-TR analysis, use function analyzeTPPTR. For a TPP-CCR analysis, use function analyzeTPPCCR. See the vignette for detailed instructions.

Value

No return value defined for this document.

References

Savitski, M. M., Reinhard, F. B., Franken, H., Werner, T., Savitski, M. F., Eberhard, D., ... & Drewes, G. (2014). Tracking cancer drugs in living cells by thermal profiling of the proteome. Science, 346(6205), 1255784.

Franken, H, Mathieson, T, Childs, D. Sweetman, G. Werner, T. Huber, W. & Savitski, M. M. (2015), Thermal proteome profiling for unbiased identification of drug targets and detection of downstream effectors. Nature protocols 10(10), 1567-1593.


TPP documentation built on Nov. 8, 2020, 5:55 p.m.