tppccrNormalize: Normalize data from TPP-CCR experiments

In TPP: Analyze thermal proteome profiling (TPP) experiments

Description

Normalize each fold change column by its median.

Usage

tppccrNormalize(data)

Arguments

data	list of expressionSets with measurements to be normalized

Value

List of expressionSet objects storing the normalized fold changes, as well as row and column metadata. In each expressionSet S, the fold changes can be accessed by Biobase::exprs(S). Protein names can be accessed by featureNames(S). Isobaric labels and the corresponding concentrations are returned by S$label and S$concentration.

Examples

data(hdacCCR_smallExample)
tppccrData <- tppccrImport(configTable=hdacCCR_config, data = hdacCCR_data)
tppccrNorm <- tppccrNormalize(data=tppccrData)
head(Biobase::exprs(tppccrNorm[[1]]))

TPP documentation built on Nov. 8, 2020, 5:55 p.m.