tpp2dCalcFractAbundance: Calculate fractional abundance and DMSO ratio of successive...

In TPP: Analyze thermal proteome profiling (TPP) experiments

Description

Calculates fractional abundance and DMSO ratio of successive sumionareas and creates respective columns which are added two the data frame which is handed over

Usage

tpp2dCalcFractAbundance(
  configTable = NULL,
  data,
  intensityStr = NULL,
  idVar = NULL
)

Arguments

configTable	DEPCRECATED
data	data frame of TPP-CCR results (e.g. obtained by run2DTPPCCR).
intensityStr	DEPCRECATED
idVar	DEPCRECATED

Value

Data frame that was handed over with additional columns of fractional abundance and DMSO1 vs DMSO2 ratio

Examples

data(panobinostat_2DTPP_smallExample)

# Import data:
datIn <- tpp2dImport(configTable = panobinostat_2DTPP_config,
                      data = panobinostat_2DTPP_data,
                      idVar = "representative",
                      addCol = "clustername",
                      intensityStr = "sumionarea_protein_",
                      nonZeroCols = "qusm")

# View attributes of imported data (experiment infos and import arguments):
attr(datIn, "importSettings") %>% unlist
attr(datIn, "configTable")

# Compute fractional abundance:
datDMSORatio <- tpp2dCalcFractAbundance(data = datIn)
colnames(datDMSORatio)

TPP documentation built on Nov. 8, 2020, 5:55 p.m.