getPEC504Temperature: Get pEC50 for a protein of interest at a specific...

In TPP2D: Detection of ligand-protein interactions from 2D thermal profiles (DLPTP)

Description

Get pEC50 for a protein of interest at a specific temperatures (optimally the melting point of the protein)

Usage

getPEC504Temperature(fstat_df, protein, temperaturePEC50 = 60)

Arguments

fstat_df	data frame as obtained after calling getModelParamsDf, containing fitted null and alternative model parameters for each protein
protein	character string referring to the protein of interest
temperaturePEC50	temperature (numeric) at which pEC50 should be inferred

Value

numeric value specifying the pEC50 for the indicated protein and temperature

Examples

data("simulated_cell_extract_df")

model_params_df <- getModelParamsDf(
   df = filter(simulated_cell_extract_df, 
           clustername == "tp1"))

getPEC504Temperature(
    fstat_df = model_params_df, 
    protein = "tp1", 
    temperaturePEC50 = 60)

TPP2D documentation built on Nov. 8, 2020, 4:54 p.m.