plot2dTppVolcano: Plot Volcano plot of TPP2D results

In TPP2D: Detection of ligand-protein interactions from 2D thermal profiles (DLPTP)

Description

Plot Volcano plot of TPP2D results

Usage

plot2dTppVolcano(
  fdr_df,
  hits_df,
  alpha = 0.5,
  title_string = "",
  x_lim = NULL,
  y_lim = NULL,
  facet_by_obs = FALSE
)

Arguments

fdr_df	data frame obtained from 'getFDR'
hits_df	hits_df data frame obtained from 'findHits'
alpha	transparency level of plotted points
title_string	character argument handed over to ggtitle
x_lim	vector with two numerics indicating the x axis limits
y_lim	vector with two numerics indicating the y axis limits
facet_by_obs	logical indicating whether plot should be facetted by number of observations, default: FALSE

Value

a ggplot displaying a volcano plot of the results obtained after a TPP2D analysis

Examples

data("simulated_cell_extract_df")
temp_df <- simulated_cell_extract_df %>%
  filter(clustername %in% paste0("protein", 1:5)) %>%
  group_by(representative) %>%
  mutate(nObs = n()) %>%
  ungroup
example_params <- getModelParamsDf(temp_df)
example_fstat <- computeFStatFromParams(example_params)
example_null <- bootstrapNullAlternativeModel(
   df = temp_df, params_df = example_params,
   B = 2)
fdr_df <- getFDR(example_fstat, example_null)
hits_df <- findHits(fdr_df, 0.1)
plot2dTppVolcano(fdr_df = fdr_df, hits_df = hits_df)

TPP2D documentation built on Nov. 8, 2020, 4:54 p.m.