Using a normalization based upon quantiles, this function normalizes a matrix of probe level intensities.
A string specifying how the normalization should be applied. See details for more.
This method is based upon the concept of a quantile-quantile
plot extended to n dimensions. No special allowances are made for
outliers. If you make use of quantile normalization either through
please cite Bolstad et al, Bioinformatics (2003).
The type argument should be one of
"separate","pmonly","mmonly","together" which indicates whether
to normalize only one probe type (PM,MM) or both together or separately.
Ben Bolstad, bmbolstad.com
Bolstad, B (2001) Probe Level Quantile Normalization of High Density Oligonucleotide Array Data. Unpublished manuscript http://bmbolstad.com/stuff/qnorm.pdf
Bolstad, B. M., Irizarry R. A., Astrand, M, and Speed, T. P. (2003) A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Bias and Variance. Bioinformatics 19(2) ,pp 185-193. http://bmbolstad.com/misc/normalize/normalize.html