enrichTF: Transcription Factors Enrichment Analysis

As transcription factors (TFs) play a crucial role in regulating the transcription process through binding on the genome alone or in a combinatorial manner, TF enrichment analysis is an efficient and important procedure to locate the candidate functional TFs from a set of experimentally defined regulatory regions. While it is commonly accepted that structurally related TFs may have similar binding preference to sequences (i.e. motifs) and one TF may have multiple motifs, TF enrichment analysis is much more challenging than motif enrichment analysis. Here we present a R package for TF enrichment analysis which combine motif enrichment with the PECA model.

Package details

AuthorZheng Wei, Zhana Duren, Shining Ma
Bioconductor views GeneTarget GraphAndNetwork MotifAnnotation Software Transcription
MaintainerZheng Wei <[email protected]>
LicenseGPL-3
Version1.2.3
URL https://github.com/wzthu/enrichTF
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
source("https://bioconductor.org/biocLite.R")
biocLite("enrichTF")

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enrichTF documentation built on Nov. 20, 2019, 2 a.m.