This function is called internally as a single instance of the beta aggregation step in RRAa. Users should not interact with it directly.
The expected input is a list of rank statistics, and a paired alpha
argument defining which values to consider in downstream analyses (see below).
1  ct.RRAalpha(p, g.key, alpha, shuffle = FALSE, return.obj = TRUE)

p 
A single column matrix of rank statistics, with 
g.key 
data.frame with guide and gene names 
alpha 
The alpha cutoff parameter, corresponding to the Pvalue threshold or fold change proportion at which gRNAs should no longer be considered to be
differentially expressed. Alternatively, this can be provided as a logical vector of the same length as the number of rows in 
shuffle 
Logical indicating whether to shuffle the rank statistics prior to calculating the rho statistics (useful for permutation). 
return.obj 
Name of the environment to record results in, or 
Nothing, or a named list of targetlevel Pvalues, which are treated as a rho statistic in the permutation step.
Russell Bainer
1 2 3 
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