This function takes in a
resultsDF and a vector of
targets (contained in the
geneID column of
resultsDF) and determines whether the specified targets are enriched within the set of all significantly altered targets.
It does this by iteratively testing whether
targets are more likely to be among the set of enriched or depleted targets
at various significance thresholds using a hypergeometric test. Note that the returned Hypergeometric P-values are not corrected
for multiple testing.
Returns a list detailing the
targets used in the tests, and tables indicating the results of the hypergeometric test
at various significance thresholds.
A dataframe summarizing the results of the screen, returned by the function
A character vector containing the names of the targets to be tested. Only targets contained in the
Logical indicating whether to consider guides that are enriched (default) or depleted within the screen.
Optionally, a character vector containing elements of the
A named list containing the tested target set and tables detailing the hypergeometric test results using various P-value and Q-value thresholds.
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