View CDFs of the ranked gRNAs or Targets present in a crispr screen
This function generates a plot relating the cumulative proportion of reads in each sample of a crispr screen to the abundance rank of the
underlying guides (or Targets). The purpose of this algorithm is to detect potential distortions in the library composition
that might not be properly controlled by sample normalization (see also:
An ExpressionSet object containing, at minimum, a matrix of gRNA abundances extractable with the exprs() function.
An optional sample key, supplied as an ordered factor linking the samples to experimental
A string indicating whether the individual guides should be displayed ("
An optional data.frame containing an annotation object to be used to aggregate the guides into targets. gRNAs are annotated by row,
and must minimally contain a column
A CDF plot displaying the appropriate CDF curves on the default device.
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