Description Usage Arguments Details Value Author(s) See Also Examples

Convert a design matrix in terms of individual channels to ones in terms of M-values or A-values for two-color microarray data.

1 2 |

`design` |
numeric model matrix with one row for each channel observation, i.e., twice as many rows as arrays |

If `design`

is a model matrix suitable for modelling individual log-intensities for two color microarray data, then `designI2M`

computes the corresponding model matrix for modelling M-values (log-ratios) and `designI2A`

computes the model matrix for modelling A-values (average log-intensities).

Note that the matrices `designI2M(design)`

or `designI2A(design)`

may be singular if not all of the coefficients are estimable from the M or A-values.
In that case there will be columns containing entirely zeros.

numeric model matrix with half as many rows as `design`

Gordon Smyth

`model.matrix`

in the stats package.

An overview of individual channel linear model functions in limma is given by 07.SingleChannel.

1 2 3 |

Embedding an R snippet on your website

Add the following code to your website.

For more information on customizing the embed code, read Embedding Snippets.