rep_range: Replication Timing Data as GRanges Object

In musicatk: Mutational Signature Comprehensive Analysis Toolkit

Description

Supplementary data converted from bigWig to bedgraph to GRanges, with low RFD indicating the leading strand and high RFD indicating lagging strand and removing uninformative zero RFD intervals. Timing data is 10kb bins from a colon cancer sample.

Usage

data(rep_range)

Format

An object of class "GRanges"; see [annotate_replication_strand()].

Source

GEO, <https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134225>

References

Sriramachandran, A. M. et al. (2020) Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq. ([Molecular Cell] (doi:10.1016/j.molcel.2020.03.027))

musicatk documentation built on Nov. 8, 2020, 5:16 p.m.